Standard Dose Syntax Examples
These medicationRequest examples are fully machine-readable in that they do not include any free-text instructions within either additionalInstruction, patientInstruction or text.
Examples use combinations of the following elements of the CareConnect medicationRequest and FHIR Dosage structure;
- form
- method
- doseQuantity
- frequency, period and frequencyMax
- when
- route
- site
- asNeededBoolean
- boundsDuration
- count
- event
Where clinically appropriate, each example is shown as both a dose-based and product-based instruction.
Important: Examples are not complete with respect to all required data for a CareConnect implementation but instead highlight the variety of use of the FHIR Dosage structure
Oxytetracycline, 250mg, oral, 6 hourly
Note: Product-based instruction using a VMP. Dose expressed 6 hourly.
Note: Dose-based instruction using a VTM. Dose expressed 6 hourly.
Omeprazole, 10mg, gastro-resistant, oral, once daily
Note: Product-based instruction using a VMP. Dose expressed per day.
Note: Dose-based instruction using a VTM. Dose expressed per day.
Trimethoprim, 200mg, oral, twice a day, for 3 days
Note: Product-based instruction using an AMP. Dose expressed per day. Duration of 3 days.
Note: Dose-based instruction using a VTM. Dose expressed per day. Duration of 3 days.
Sodium citrate / Micralax Micro-enema enema, once daily
Note: Product-based instruction using an AMP. Dose expressed per day.
Note: Dose-based instruction using a VTM. Dose expressed per day.
Diprobase ointment, 1 application, Topical, 3 times a day
Note: Product-based instruction using an AMP. Where no dose quantity.
Note: Dose-based instruction using a VTM. Where no dose quantity.
The VTM related to the Diprobase AMP’s is a multi-ingredient concept “White soft paraffin + Liquid paraffin” and cannot be used as a prescribing concept.
Beclometasone 0.025% cream, Apply Thigh, twice a day
Note: Product-based instruction using a VMP. Body site identified.
Note: Dose-based instruction using a VTM. Body site identified.
Where a concentration is required it is expected that the prescribing concept would be a VMP or AMP.
Zopiclone 3.75mg tablets, 1 tablet, at BEDTIME, PRN, oral
Note: Product-based instruction using a VMP. When required dosing.
Ibuprofen 400mg orally three times daily for 5 days to start tomorrow
For this example, assume today’s date is 9th March 2019, hence ‘tomorrow’ is 10th March 2019.
Note: Dose-based instruction using a VTM. Specified start date and course length.
Timolol 0.1% gel eye drops, 1 drop in the left eye once daily
Note: Product-based instruction using a VMP. Body site identified.
Epoetin alfa, 4500units, ONCE a DAY, subcutaneous injection
Note: Dose-based instruction using a VTM. Route and method identified.
Morphine modified release capsule, 20mg orally every 12 hours
Note: Dose-based instruction using a VTM with a specific form. Dose expressed as hourly dose interval.
Morphine, 30mg, intravenously, injection, four times a day, for 1 day
Note: Dose-based instruction using a VTM. Route and method identified and course duration.
Zoladex 3.6mg implant SafeSystem pre-filled syringes (AstraZeneca UK Ltd), one to be given by IM injection into the anterior abdominal wall on 1st November 2019
Note: Product-based instruction using an AMP. Identified route, method and site. Specific date.
Hyoscine 1mg/72hours transdermal patches, one patch to be applied once every 3 days
Note: Product-based instruction using a VMP. Dosing every 3 days. Specific method.
Co-trimoxazole 80mg/400mg tablets (Actavis UK Ltd), one tablet to be taken twice daily on Mondays, Wednesdays and Fridays
Note: Product-based instruction using an AMP. Dosing given only on specific days.
Furosemide 40mg tablets, take two in the morning and one at midday for one week
Note: Product based presciption demonstrating concurrent dosing schedules.
Metformin 500mg tablets, initially 500 mg once daily for 1 week, dose to be taken with breakfast, then 500 mg twice daily for week, dose to be taken with breakfast and evening meal, then 500 mg 3 times a day, dose to be taken with breakfast, lunch and evening meal; maximum 2 g per day
Note: Product based presciption demonstrating sequential dosing schedules for an increasing dose.
Metoclopramide, orally 10mg to be taken when required for nausea up to three times daily
Note: Dose based prescription with when required dosing and daily maximum frequency
Aspirin suppository, 600mg rectally every 4 hours. Maximum 3.6gm per 24 hours
Note: Dose based prescription with maximum dose.
Glucose 5% infusion 500ml bags, 500ml, intravenous, continuous infusion, over 8 hours
Note: Product based prescription. Route, method and dose duration.
Glucose 5% infusion, intravenous, 100ml/hour, continuous infusion, over 8 hours
Note: Non dm+d (ingredient) based prescription. Route, method and dose duration.
Voluven 10% infusion 500ml Freeflex bags (Fresenius Kabi Ltd), infuse intravenously at a rate of 30ml/kg for 10 hours
Includes a rateRatio and a duration.
Note: Product based prescription. Route method,dose duration, and dose expressed a rate ratio.
Note. The rateRatio could also be modelled using a UCUM unit within a doseQuantity. In this example we are using the slightly more complex rateRatio structure.
<doseQuantity>
<value value="30"/>
<unit value="millilitres per kilogram"/>
<system value="http://unitsofmeasure.org"/>
<code value="ml/kg"/>
</doseQuantity>
Hydroxocobalamin 10mg/2ml solution for injection ampoules, one to be given by IM injection into the shoulder, 3 times per week for 6 doses, then every 3 months, starting on 1st November 2019
Note: Product based prescription with course length as number of doses, sequential dosing.
